Donkey Kong 64 (abbreviated as DK 64) is a platformer video game developed by Rare and published by Nintendo for the Nintendo 64. It was released in North America on November 22, 1999 and in Europe on December 6, 1999. The game is a follow up to the Donkey Kong Country trilogy on the Super Nintendo Entertainment System. Donkey Kong 64 follows the adventures of the titular Donkey Kong and four of his simian relatives as they try to win back their hoard of Golden Bananas and banish the evil King K.Rool and his cronies from the vicinity of their island. Players can control all five Kongs in eight individual levels as well as a greater worldmap, a multiplayer mode, and several minigames.

Doom 64 is a video game for the Nintendo 64 released by Midway Games in 1997. It is part of the Doom first-person shooter video game series.

Dr. Mario 64 is a puzzle game based on the original Dr. Mario. It was developed by Newcome and published by Nintendo, released for the Nintendo 64 in 2001, and is an enhanced remake of the original Dr. Mario, which was released for the NES and Game Boy in 1990.

120 years ago, in preparation for the coming doom, mankind began an exodus to the manmade satellites in outer space. But the "Day of Judgment" arrived even before half the population had escaped to space. The shift in the tectonic plate caused the shape of the Pacific Ocean to change and a new continent was created.

After 100 years, the only inhabitable areas were limited to the area around the new Pacific Ocean and the new continent. New nations were founded on this continent and mankind began rebuilding their lives. In the midst of rebuilding, "Gaiathyst" a mineral which releases an energy similar to gravity was discovered as a new source of endless energy.

Duke Nukem: Zero Hour is a third-person shooter video game in the Duke Nukem series, developed by Eurocom for the Nintendo 64. The game uses a relatively large 32 megabyte cartridge and could also utilize the Expansion Pak to allow for better graphics but slowing down the frame rate. It has a 4 player split-screen multiplayer mode that uses a first-person view.

Duke Nukem 64 is a Nintendo 64 port of the first-person shooter PC (MS-DOS) video game Duke Nukem 3D. There are many changes from the PC version. For instance, some weapons use two different types of ammo and many of the original game's mature themes have been watered down.

Earthworm Jim 3D is to date the last console game in the Earthworm Jim series. Created by Interplay and based more on the Television series than the canon of the previous games, Earthworm Jim 3D was released for Nintendo 64 and PC. While the game featured classic villains such as Psy-Crow and Professor Monkey-For-A-Head, it was criticized for falsely advertising on the game box that Evil the Cat was included. This omission was due to a rushed development cycle, leading to the removal of a number of game locations (some also appearing on the game box) in an attempt to meet the game's release date. And as such, a planned PlayStation version of the game was cancelled.