To get AOX in Chrome see this
http://retrouprising.com/support/ret.../chrome/t9856/
Flash wont work in IE64 making it almost useless.
There would be nothing server side that would cause your IE not to work on multiple sites.
You are saying you start IE and it opens and then immediately closes? Do you get an error message?
Likely causes would be your homepage, a plug in, a virus or some deleted files that IE needs.
First try running without any plugins.
Go to Start > Run (if you don't see it press the Windows Key + R)
Type iexplore -extoff
Press Enter
Did that work? If yes then problem is probably an addon. Try removing them one at a time until you find the problem one.