2 Stupid Dogs was about two dogs and their everyday strange and funny mishappenings, with an animation style that was unusual (at the time); a very flat, simplistic style similar to early Hanna-Barbera cartoons of the 1950s and 60s, with early 1990s humor and sensibility. It also did not have a series structure, similar to many humorous cartoons and sitcoms. (i.e. the show does not follow a continuous storyline, what happens in one episode has little to no effect on another).

2 Stupid Dogs was the beginning of the successful revival of Hanna-Barbera's fortunes, since the studio had not launched a bona fide hit since The Smurfs in 1981.

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